Reactome Pathway Database

Schema > BlackBoxEvent > Entries

AFG3L2:SPG7 degrades SMDT1 (EMRE) Show undefined attributes

catalystActivity

[CatalystActivity:10193223] ATP-dependent peptidase activity of AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane]

category omitted

compartment

[Compartment:70616] mitochondrial inner membrane

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10193225

displayName AFG3L2:SPG7 degrades SMDT1 (EMRE)

eventOf

[Pathway:R-RNO-9837999] Mitochondrial protein degradation - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-9839059] AFG3L2:SPG7 degrades SMDT1 (EMRE) - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AFG3L2:SPG7 degrades SMDT1 (EMRE)

output

precedingEvent

[Reaction:R-RNO-9839053] AFG3L2:SPG7 binds SMDT1 (EMRE) - Rattus norvegicus

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:48895] Rattus norvegicus

stId R-RNO-9839059

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-9837999] Mitochondrial protein degradation

(inferredTo)

[BlackBoxEvent:R-HSA-9839059] AFG3L2:SPG7 degrades SMDT1 (EMRE)

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