Reactome Pathway Database

Schema > Reaction > Entries

PRKACA phosphorylates TFAM in the mitochondrial matrix Show undefined attributes

catalystActivity

[CatalystActivity:10193204] cAMP-dependent protein kinase activity of PRKACA [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10193206

displayName PRKACA phosphorylates TFAM in the mitochondrial matrix

eventOf

[Pathway:R-RNO-9837999] Mitochondrial protein degradation - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-RNO-9838093] LONP1 binds mitochondrial matrix proteins - Rattus norvegicus

inferredFrom

[Reaction:R-HSA-9838321] PRKACA phosphorylates TFAM in the mitochondrial matrix - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PRKACA phosphorylates TFAM in the mitochondrial matrix

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-9838321

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-9837999] Mitochondrial protein degradation

(precedingEvent)

[Reaction:R-RNO-9838093] LONP1 binds mitochondrial matrix proteins

(inferredTo)

[Reaction:R-HSA-9838321] PRKACA phosphorylates TFAM in the mitochondrial matrix

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