Reactome Pathway Database

Schema > Reaction > Entries

dUTP + H2O => dUMP + pyrophosphate Show undefined attributes

catalystActivity

[CatalystActivity:10089088] dUTP diphosphatase activity of DUT trimer [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10089090

displayName dUTP + H2O => dUMP + pyrophosphate

eventOf

[Pathway:R-RNO-499943] Interconversion of nucleotide di- and triphosphates - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-RNO-73605] dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate - Rattus norvegicus

inferredFrom

[Reaction:R-HSA-73666] dUTP + H2O => dUMP + pyrophosphate - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

dUTP + H2O => dUMP + pyrophosphate
hydrolysis of 2'-deoxyuridine 5'-triphosphate to form 2'-deoxyuridine 5'-phosphate

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-73666

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-499943] Interconversion of nucleotide di- and triphosphates

(precedingEvent)

[Reaction:R-RNO-73605] dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate

(inferredTo)

[Reaction:R-HSA-73666] dUTP + H2O => dUMP + pyrophosphate

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