Reactome Pathway Database

Schema > Reaction > Entries

N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate Show undefined attributes

catalystActivity

[CatalystActivity:9967670] formimidoyltetrahydrofolate cyclodeaminase activity of FTCD octamer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9967672

displayName N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate

eventOf

[Pathway:R-MMU-70921] Histidine catabolism - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-70920] N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate
(6S)-5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate => 5-formimidoyltetrahydrofolate + L-glutamate

output

precedingEvent

[Reaction:R-MMU-70906] 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-70920

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-70921] Histidine catabolism

(inferredTo)

[Reaction:R-HSA-70920] N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate

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