Reactome Pathway Database

Schema > Reaction > Entries

glutamate uptake by astrocytes Show undefined attributes

catalystActivity

[CatalystActivity:9987581] amino acid transmembrane transporter activity of Astrocytic EAATs [plasma membrane]

category transition

compartment

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9987583

displayName glutamate uptake by astrocytes

eventOf

[Pathway:R-MMU-210455] Astrocytic Glutamate-Glutamine Uptake And Metabolism - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-MMU-70606] glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] - Mus musculus

inferredFrom

[Reaction:R-HSA-210439] glutamate uptake by astrocytes - Homo sapiens

input

[SimpleEntity:R-ALL-210382] L-Glu [extracellular region]

isInDisease false

isInferred true

maxDepth 1

name

glutamate uptake by astrocytes

output

[SimpleEntity:R-ALL-29404] L-Glu [cytosol]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-210439

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-210455] Astrocytic Glutamate-Glutamine Uptake And Metabolism

(precedingEvent)

[Reaction:R-MMU-70606] glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]

(inferredTo)

[Reaction:R-HSA-210439] glutamate uptake by astrocytes

© 2025 Reactome

Cite Us!