Reactome Pathway Database

Schema > Reaction > Entries

UCP1 imports a proton Show undefined attributes

catalystActivity

[CatalystActivity:9978046] proton transmembrane transporter activity of UCP1 dimer [mitochondrial inner membrane]

category transition

compartment

[Compartment:70616] mitochondrial inner membrane

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 9978048

displayName UCP1 imports a proton

eventOf

[Pathway:R-MMU-166187] Mitochondrial Uncoupling - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-170026] UCP1 imports a proton - Homo sapiens

input

[SimpleEntity:R-ALL-163953] H+ [mitochondrial intermembrane space]

isInDisease false

isInferred true

maxDepth 1

name

UCP1 imports a proton
Protons are translocated from the intermembrane space to the matrix

output

[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]

precedingEvent

regulatedBy

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-170026

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-166187] Mitochondrial Uncoupling

(inferredTo)

[Reaction:R-HSA-170026] UCP1 imports a proton

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