Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
KIT V560E [plasma membrane]
Show undefined attributes
Go to Details
candidateOf
[CandidateSet:R-HSA-9669757] juxtamembrane domain KIT mutants [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9681384] ripretinib-sensitive KIT mutants [plasma membrane] - Homo sapiens
compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane] - Homo sapiens
created
[InstanceEdit:9669567] Rothfels, Karen, 2019年12月03日
crossReference
[DatabaseIdentifier:11944977] Mondo:0011719
[DatabaseIdentifier:11944892] Mondo:0004992
[DatabaseIdentifier:9669329] COSMIC:COSM22425
[DatabaseIdentifier:9669309] COSMIC:COSV55390849
dbId
9669566
disease
[Disease:9661830] gastrointestinal stromal tumor
[Disease:1500689] cancer
displayName
KIT V560E [plasma membrane]
endCoordinate
976
hasModifiedResidue
[ReplacedResidue:9669530] L-valine 560 replaced with L-glutamic acid
inDisease
true
maxDepth
1
memberOf
[DefinedSet:R-HSA-9669841] sunitinib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669825] regorafenib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669834] sorafenib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669768] nilotanib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669766] masitinib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669742] dovitinib sensitive KIT mutants [plasma membrane] - Homo sapiens
[DefinedSet:R-HSA-9669750] imatinib sensitive KIT mutants [plasma membrane] - Homo sapiens
name
KIT V560E
Mast/stem cell growth factor receptor precursor
KIT_HUMAN
c-KIT
referenceEntity
[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9669566
startCoordinate
26
Referrals
(hasCandidate)
[CandidateSet:R-HSA-9669757] juxtamembrane domain KIT mutants [plasma membrane]
[CandidateSet:R-HSA-9681384] ripretinib-sensitive KIT mutants [plasma membrane]
(hasComponent)
[Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane]
(hasMember)
[DefinedSet:R-HSA-9669768] nilotanib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669834] sorafenib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669766] masitinib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669750] imatinib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669825] regorafenib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669841] sunitinib sensitive KIT mutants [plasma membrane]
[DefinedSet:R-HSA-9669742] dovitinib sensitive KIT mutants [plasma membrane]
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル