Reactome Pathway Database

Schema > Complex > Entries

ERBB2 ECD mutants:EGF:EGFR [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:9665390] protein tyrosine kinase activity of ERBB2 ECD mutants:EGF:EGFR [plasma membrane]

compartment

[Compartment:876] plasma membrane

consumedByEvent

[Reaction:R-HSA-9665389] Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate - Homo sapiens

created [InstanceEdit:9665383] Orlic-Milacic, Marija, 2019年10月30日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9665391

disease

[Disease:1500689] cancer

displayName ERBB2 ECD mutants:EGF:EGFR [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:984] extracellular region

isChimeric false

maxDepth 3

name

ERBB2 ECD mutants:EGF:EGFR

producedByEvent

[Reaction:R-HSA-9665388] ERBB2 ECD mutants heterodimerize with EGFR - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-9665391

Referrals

(output)

[Reaction:R-HSA-9665388] ERBB2 ECD mutants heterodimerize with EGFR

(input)

[Reaction:R-HSA-9665389] Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate

(diseaseEntity)

[EntityFunctionalStatus:9665387] gain_of_function of ERBB2 ECD mutants:EGF:EGFR [plasma membrane]

(physicalEntity)

[CatalystActivity:9665390] protein tyrosine kinase activity of ERBB2 ECD mutants:EGF:EGFR [plasma membrane]

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