Reactome Pathway Database

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EGF-like ligands:EGFR dimer [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:9624430] protein tyrosine kinase activity of EGF-like ligands:EGFR dimer [plasma membrane]

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-1225979] EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane] - Homo sapiens

consumedByEvent

[Reaction:R-HSA-1225978] Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers - Homo sapiens
[Reaction:R-HSA-177934] EGFR autophosphorylation - Homo sapiens
[Reaction:R-HSA-177937] Phosphorylation of EGFR by SRC kinase - Homo sapiens

created [InstanceEdit:9624421] Rothfels, Karen, 2018年10月11日

dbId 9624420

displayName EGF-like ligands:EGFR dimer [plasma membrane]

hasComponent

2 × [Complex:R-HSA-9624419] EGFR:EGF-like ligands [plasma membrane]

inDisease false

includedLocation

[Compartment:984] extracellular region

inferredTo

isChimeric false

maxDepth 4

name

EGF-like ligands:EGFR dimer

producedByEvent

[Reaction:R-HSA-177922] EGFR dimerization - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-9624420

Referrals

(hasComponent)

[Complex:R-HSA-1225979] EGF-like ligands:EGFR Dimer:Covalent EGFR TKIs [plasma membrane]

(input)

(normalEntity)

(physicalEntity)

[CatalystActivity:9624430] protein tyrosine kinase activity of EGF-like ligands:EGFR dimer [plasma membrane]

(output)

[Reaction:R-HSA-177922] EGFR dimerization

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