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Schema
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Reaction
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Entries
YRDC synthesizes threonylcarbamoyladenylate
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authored
[InstanceEdit:9611207] May, Bruce, 2018年06月17日
catalystActivity
[CatalystActivity:9611200] L-threonylcarbamoyladenylate synthase activity of YRDC [mitochondrial matrix]
catalystActivityReference
[CatalystActivityReference:9643214] L-threonylcarbamoyladenylate synthase activity of YRDC [mitochondrial matrix] CO
2
-sensitive tRNA modification associated with human mitochondrial disease
category
transition
compartment
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:9611202] May, Bruce, 2018年06月18日
dbId
9611218
displayName
YRDC synthesizes threonylcarbamoyladenylate
edited
[InstanceEdit:9611207] May, Bruce, 2018年06月17日
eventOf
[Pathway:R-HSA-6787450] tRNA modification in the mitochondrion - Homo sapiens
followingEvent
[Reaction:R-HSA-9611197] OSGEPL1 threonylcarbamoylates adenosine-37 in tRNA - Homo sapiens
input
[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix]
[SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix]
[SimpleEntity:R-ALL-379706] L-Thr [mitochondrial matrix]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9611227] CO
2
-sensitive tRNA modification associated with human mitochondrial disease
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
YRDC synthesizes threonylcarbamoyladenylate
orthologousEvent
[Reaction:R-CEL-9611218] YRDC synthesizes threonylcarbamoyladenylate - Caenorhabditis elegans
[Reaction:R-DME-9611218] YRDC synthesizes threonylcarbamoyladenylate - Drosophila melanogaster
[Reaction:R-GGA-9611218] YRDC synthesizes threonylcarbamoyladenylate - Gallus gallus
[Reaction:R-XTR-9611218] YRDC synthesizes threonylcarbamoyladenylate - Xenopus tropicalis
[Reaction:R-DRE-9611218] YRDC synthesizes threonylcarbamoyladenylate - Danio rerio
[Reaction:R-SSC-9611218] YRDC synthesizes threonylcarbamoyladenylate - Sus scrofa
[Reaction:R-BTA-9611218] YRDC synthesizes threonylcarbamoyladenylate - Bos taurus
[Reaction:R-CFA-9611218] YRDC synthesizes threonylcarbamoyladenylate - Canis familiaris
[Reaction:R-RNO-9611218] YRDC synthesizes threonylcarbamoyladenylate - Rattus norvegicus
[Reaction:R-MMU-9611218] YRDC synthesizes threonylcarbamoyladenylate - Mus musculus
output
[SimpleEntity:R-ALL-9611204] L-threonylcarbamoyladenylate [mitochondrial matrix]
releaseDate
2025年06月18日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9939458] Zhou, Xiao-Long, 2025年02月27日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-9611218
summation
[Summation:9611247] In vitro, YRDC and OSGEPL1 catalyze the threonylcarbamoylati...
Referrals
(precedingEvent)
[Reaction:R-HSA-9611197] OSGEPL1 threonylcarbamoylates adenosine-37 in tRNA
(hasEvent)
[Pathway:R-HSA-6787450] tRNA modification in the mitochondrion
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