Reactome Pathway Database

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AGER binds ERK1/2 Show undefined attributes

authored

[InstanceEdit:849794] Jupe, S, 2010年06月01日

category binding

compartment

created [InstanceEdit:879462] Jupe, S, 2010年06月17日

dbId 879362

displayName AGER binds ERK1/2

edited

[InstanceEdit:1020099] Jupe, S, 2010年11月16日

eventOf

[Pathway:R-HSA-879415] Advanced glycosylation endproduct receptor signaling - Homo sapiens

inferredFrom

[Reaction:R-NUL-997411] AGER binds rat ERK1/2 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred true

literatureReference

[LiteratureReference:879440] The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

AGER binds ERK1/2

output

[Complex:R-HSA-879427] AGER ligands:AGER:ERK [plasma membrane]

precedingEvent

[Reaction:R-HSA-879411] Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor - Homo sapiens

releaseDate 2010年12月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:997390] Yan, SD, 2010年11月09日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-879362

summation

[Summation:997396] Binding of ligand to AGER results in the activation of multi...

Referrals

(hasEvent)

[Pathway:R-HSA-879415] Advanced glycosylation endproduct receptor signaling

(inferredTo)

[Reaction:R-NUL-997411] AGER binds rat ERK1/2

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