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The Ligand:GPCR:G12/13 complex dissociates Show undefined attributes

authored

[InstanceEdit:744889] Jupe, S, 2010年05月18日

category dissociation

compartment

created [InstanceEdit:751025] Jupe, S, 2010年05月19日

dbId 751019

displayName The Ligand:GPCR:G12/13 complex dissociates

edited

[InstanceEdit:813668] Jupe, S, 2010年05月26日

eventOf

[Pathway:R-HSA-416482] G alpha (12/13) signalling events - Homo sapiens

followingEvent

[Reaction:R-HSA-8964274] G alpha (12) binds BTK - Homo sapiens
[Reaction:R-HSA-418574] G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP - Homo sapiens
[Reaction:R-HSA-398184] LARG activation by G alpha 12/13 - Homo sapiens
[Reaction:R-HSA-114548] G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) - Homo sapiens
[Reaction:R-HSA-392295] Gbeta:gamma recruits PI3K gamma - Homo sapiens
[Reaction:R-HSA-8964241] G beta-gamma complex and PIP3 recruit BTK to membrane - Homo sapiens
[Reaction:R-HSA-398040] Gbeta:gamma activation of PLC beta - Homo sapiens
[Reaction:R-HSA-8964605] PAK1:ARHGEF6 complex binds G-protein beta-gamma complex - Homo sapiens

input

[Complex:R-HSA-751015] Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:427945] Dissociation of heterotrimeric g proteins in cells

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

The Ligand:GPCR:G12/13 complex dissociates

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-751029] Liganded G12/13-activating GPCR acts as a GEF for G12/13 - Homo sapiens

releaseDate 2010年06月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:782850] D'Eustachio, P, 2010年05月21日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-751019

summation

[Summation:804947] The classical view of G-protein signalling is that the G-pro...

Referrals

(precedingEvent)

(hasEvent)

[Pathway:R-HSA-416482] G alpha (12/13) signalling events

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