Reactome Pathway Database

Schema > Reaction > Entries

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ Show undefined attributes

catalystActivity

[CatalystActivity:74155] 3-hydroxybutyrate dehydrogenase activity of BDH1 tetramer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:77113] Gopinathrao, G, 2003年10月16日 18:43:13

crossReference

[DatabaseIdentifier:12611320] Rhea:20522

dbId 73920

displayName D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

eventOf

[Pathway:R-HSA-77108] Utilization of Ketone Bodies - Homo sapiens

followingEvent

[Reaction:R-HSA-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:200046] Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart

maxDepth 1

modified [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

name

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

orthologousEvent

output

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-73920

summation

[Summation:178628] D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the ...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-77108] Utilization of Ketone Bodies

(precedingEvent)

[Reaction:R-HSA-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA

(reverseReaction)

[Reaction:R-HSA-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+

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