Reactome Pathway Database

Schema > Complex > Entries

Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:5655273] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:5655319] Rothfels, Karen, 2014年12月05日

crossReference

dbId 5655294

disease

displayName Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:70101] cytosol

isChimeric false

literatureReference

maxDepth 7

modified [InstanceEdit:9753857] Rothfels, Karen, 2021年09月15日

name

Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K

producedByEvent

[Reaction:R-HSA-5655285] Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-5655294

updateTrackers

Referrals

(updatedInstance)

(diseaseEntity)

[EntityFunctionalStatus:5655286] gain_of_function of Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

(physicalEntity)

[CatalystActivity:5655273] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

(output)

[Reaction:R-HSA-5655285] Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA

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