Reactome Pathway Database

Schema > Complex > Entries

DDIT4:14-3-3 dimer [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:5632737] Orlic-Milacic, Marija, 2014年10月28日

dbId 5632741

displayName DDIT4:14-3-3 dimer [cytosol]

hasComponent

inDisease false

inferredTo

isChimeric false

literatureReference

[LiteratureReference:5632740] Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
[LiteratureReference:5632356] p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage

maxDepth 4

modified [InstanceEdit:5632746] Orlic-Milacic, Marija, 2014年10月28日

name

DDIT4:14-3-3 dimer

negativelyRegulates

[NegativeRegulation:R-HSA-5632745] Negative regulation by 'DDIT4:14-3-3 dimer [cytosol]'

producedByEvent

[Reaction:R-HSA-5632738] DDIT4 binds 14-3-3 dimer - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-5632741

updateTrackers

Referrals

(updatedInstance)

(regulator)

[NegativeRegulation:R-HSA-5632745] Negative regulation by 'DDIT4:14-3-3 dimer [cytosol]'

(output)

[Reaction:R-HSA-5632738] DDIT4 binds 14-3-3 dimer

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