Reactome Pathway Database

Schema > Reaction > Entries

5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol Show undefined attributes

authored

[InstanceEdit:193783] D'Eustachio, P, 2007年02月23日 20:35:09

catalystActivity

[CatalystActivity:192098] alcohol dehydrogenase (NADP+) activity of Aldo-keto reductase family [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:193768] D'Eustachio, P, 2007年02月23日 20:48:08

dbId 193758

displayName 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol

edited

[InstanceEdit:193783] D'Eustachio, P, 2007年02月23日 20:35:09

eventOf

[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Homo sapiens

followingEvent

[Reaction:R-HSA-193715] 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:192140] Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution

maxDepth 1

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol
5beta-cholestan-7alpha,24(S)-diol-3-one+ NADPH + H+ => 5beta-cholestan-3alpha,7alpha,24(S)-triol + NADP+

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-193746] 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one - Homo sapiens

releaseDate 2007年05月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-193758

summation

[Summation:193759] 5Beta-cholesten-7alpha,24(S)-diol-3-one and NADPH + H+ form ...

updateTrackers

[UpdateTracker:9791969] Update Tracker - [Reaction:193758] 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol - v24:[add_removeOutput]

Referrals

(updatedInstance)

[UpdateTracker:9791969] Update Tracker - [Reaction:193758] 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol - v24:[add_removeOutput]

(hasEvent)

[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol

(precedingEvent)

[Reaction:R-HSA-193715] 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix

© 2025 Reactome

Cite Us!