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4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one Show undefined attributes

authored

[InstanceEdit:193783] D'Eustachio, P, 2007年02月23日 20:35:09

catalystActivity

[CatalystActivity:192006] alcohol dehydrogenase (NADP+) activity of AKR1D1 [cytosol]

category transition

compartment

created [InstanceEdit:193768] D'Eustachio, P, 2007年02月23日 20:48:08

dbId 193755

displayName 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one

edited

[InstanceEdit:193783] D'Eustachio, P, 2007年02月23日 20:35:09

eventOf

[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Homo sapiens

followingEvent

[Reaction:R-HSA-193781] 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:192039] Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme

maxDepth 1

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one
4-cholesten-7alpha,12alpha,24(S)-triol-3-one + NADPH + H+ => 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one + NADP+

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-193709] CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL - Homo sapiens

releaseDate 2007年05月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-193755

summation

[Summation:193790] 4-cholesten-7alpha,12alpha,24(S)-triol-3-one and NADPH + H+ ...

Referrals

(hasEvent)

[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol

(precedingEvent)

[Reaction:R-HSA-193781] 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol

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