Reactome Pathway Database

Schema > BlackBoxEvent > Entries

Lyn activates ERK Show undefined attributes

authored

[InstanceEdit:976955] Jupe, S, 2010年10月14日

catalystActivity

[CatalystActivity:1168926] non-membrane spanning protein tyrosine kinase activity of Growth Hormone:Growth Hormone Receptor-JAK2 dimer:LYN [plasma membrane]

category omitted

compartment

[Compartment:70101] cytosol

created [InstanceEdit:1168454] Jupe, S, 2010年12月22日

dbId 1168459

displayName Lyn activates ERK

edited

[InstanceEdit:1362504] Jupe, S, 2011年06月10日

eventOf

[Pathway:R-HSA-982772] Growth hormone receptor signaling - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:1168395] An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Lyn activates ERK

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-1168456] Growth hormone receptor binds Lyn - Homo sapiens

releaseDate 2011年09月20日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-1168459

summation

[Summation:1168455] The activation of Lyn by GHR is thought to indirectly activa...

Referrals

(hasEvent)

[Pathway:R-HSA-982772] Growth hormone receptor signaling

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