Reactome Pathway Database

Schema > Reaction > Entries

ALDH4A1 oxidises L-GluSS to Glu Show undefined attributes

catalystActivity

[CatalystActivity:10681716] L-glutamate gamma-semialdehyde dehydrogenase activity of ALDH4A1 dimer [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10681718

displayName ALDH4A1 oxidises L-GluSS to Glu

eventOf

[Pathway:R-GGA-70688] Proline catabolism - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-70679] ALDH4A1 oxidises L-GluSS to Glu - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ALDH4A1 oxidises L-GluSS to Glu
H2O + L-glutamate 5-semialdehyde + NAD(+) => 2 H(+) + L-glutamate + NADH
L-glutamate gamma-semialdehyde + NAD+ => glutamate + NADH + H+

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-70679

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-70688] Proline catabolism

(inferredTo)

[Reaction:R-HSA-70679] ALDH4A1 oxidises L-GluSS to Glu

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