Reactome Pathway Database

Schema > Reaction > Entries

Mitochondrial FPGS-1 transforms THF to THFPG Show undefined attributes

catalystActivity

[CatalystActivity:10696338] tetrahydrofolylpolyglutamate synthase activity of FPGS-1 [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10696340

displayName Mitochondrial FPGS-1 transforms THF to THFPG

eventOf

[Pathway:R-GGA-196757] Metabolism of folate and pterines - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-200682] Mitochondrial FPGS-1 transforms THF to THFPG - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Mitochondrial FPGS-1 transforms THF to THFPG
Conversion of mitochondrial THF to THF-polyglutamate

output

precedingEvent

[Reaction:R-GGA-200680] SLC25A32 transports THF from cytosol to mitochondrial matrix - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-200682

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-196757] Metabolism of folate and pterines

(inferredTo)

[Reaction:R-HSA-200682] Mitochondrial FPGS-1 transforms THF to THFPG

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