Reactome Pathway Database

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(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol Show undefined attributes

catalystActivity

[CatalystActivity:10969720] inositol bisdiphosphate tetrakisphosphate diphosphatase activity of NUDT(1) [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

dbId 10969722

displayName (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol

eventOf

[Pathway:R-DDI-1855167] Synthesis of pyrophosphates in the cytosol - Dictyostelium discoideum

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-1855165] (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

(PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol

output

precedingEvent

[Reaction:R-DDI-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Dictyostelium discoideum

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:170941] Dictyostelium discoideum

stId R-DDI-1855165

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DDI-1855167] Synthesis of pyrophosphates in the cytosol

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-1855165] (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol

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