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Schema
>
LiteratureReference
>
Entries
PDGFRA activating mutations in gastrointestinal stromal tumors
Show undefined attributes
author
[Person:9669096] Heinrich, MC
[Person:9629839] Corless, CL
[Person:5686660] Duensing, A
[Person:9669212] McGreevey, L
[Person:9671899] Chen, CJ
[Person:9671897] Joseph, N
[Person:9671433] Singer, S
[Person:9671430] Griffith, DJ
[Person:9669217] Haley, A
[Person:9669216] Town, A
[Person:9669081] Demetri, GD
[Person:9671895] Fletcher, CD
[Person:9669087] Fletcher, JA
created
[InstanceEdit:9671896] Rothfels, Karen, 2019年12月23日
dbId
9671898
displayName
PDGFRA activating mutations in gastrointestinal stromal tumors
journal
Science
pages
708-10
pubMedIdentifier
12522257
schemaClass
LiteratureReference
title
PDGFRA activating mutations in gastrointestinal stromal tumors
url
http://www.ncbi.nlm.nih.gov/pubmed/12522257
volume
299
year
2003
Referrals
(literatureReference)
[Pathway:R-HSA-9674415] Drug resistance of PDGFR mutants
[FailedReaction:R-HSA-9674397] Imatinib-resistant PDGFR mutants don't bind imatinib
[Reaction:R-HSA-9672170] SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors
[Reaction:R-HSA-9672164] GRB2:SOS1 complex binds to mutant PDGFR receptor
[Reaction:R-HSA-9672176] STAT binds to the mutant PDGFRA receptor
[Reaction:R-HSA-9672177] PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR
[Reaction:R-HSA-9672172] PI3-kinase binds to mutant PDGFR receptor
[Reaction:R-HSA-9672175] Autophosphorylation of PDGFR mutant dimers
[Reaction:R-HSA-9672168] Ligand-independent dimerization of PDGFR mutants
(author)
[Person:9629839] Corless, CL
[Person:9669096] Heinrich, MC
[Person:9671433] Singer, S
[Person:9671430] Griffith, DJ
[Person:9669216] Town, A
[Person:9669217] Haley, A
[Person:5686660] Duensing, A
[Person:9669212] McGreevey, L
[Person:9669087] Fletcher, JA
[Person:9669081] Demetri, GD
[Person:9671897] Joseph, N
[Person:9671899] Chen, CJ
[Person:9671895] Fletcher, CD
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