Reactome Pathway Database

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1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] Show undefined attributes

activeUnit

[EntityWithAccessionedSequence:R-HSA-74787] PIK3CA [cytosol] - Homo sapiens

activity [GO_MolecularFunction:78763] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

catalyzedEvent

[Reaction:R-HSA-5655323] Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 - Homo sapiens

created [InstanceEdit:5655319] Rothfels, Karen, 2014年12月05日

dbId 5655329

displayName 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

modified [InstanceEdit:9963749] Weiser, Joel, 2025年08月15日

physicalEntity [Complex:R-HSA-5655337] Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

schemaClass CatalystActivity

Referrals

(catalystActivity)

[Reaction:R-HSA-5655323] Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3

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