dbId
425753
displayName
Phospholipase C beta (PLCbeta) isoforms are activated by G-p...
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Summation
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Phospholipase C beta (PLCbeta) isoforms are activated by G-protein beta:gamma in the order PLCB3> PLCB2> PLCB1. Gbeta:gamma binds to the pleckstrin homology domain of PLC beta, increasing phospholipase activity and leading to increased hydrolysis of PIP2 to DAG and IP3.