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chronic myeloid leukemia Show undefined attributes

created [InstanceEdit:1247686] Orlic-Milacic, Marija, 2011年04月05日

databaseName DOID

dbId 1247687

displayName chronic myeloid leukemia

identifier 8552

name

chronic myeloid leukemia

referenceDatabase [ReferenceDatabase:1247631] DOID

schemaClass Disease

synonym

CML
chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)
chronic myeloid leukemia, disease (disorder)
chronic myeloid leukemia without mention of remission
CML - chronic Myelogenous Leukemia
chronic myeloid leukemia in remission (disorder)
Myeloid Leukemia, chronic
CML in Remission
chronic myeloid leukemia in remission
chronic myeloid leukaemia
chronic myeloid leukemia NOS (disorder)

url https://www.ebi.ac.uk/ols/ontologies/doid/terms?obo_id=DOID:8552

Referrals

(disease)

[EntityWithAccessionedSequence:R-HSA-9632256] p16INK4A T77S [cytosol]
[Complex:R-HSA-9673933] p-12Y ETV6(1-154)-PDGFRB(527-1106) fusion dimer [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9673912] p-12Y-ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
[Complex:R-HSA-9673914] ETV6(1-154)-PDGFRB(527-1106) fusion dimer [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9673893] ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
[Complex:R-HSA-9674328] PDGFRA D842L dimer [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9674303] PDGFRA D842L [plasma membrane]
[Complex:R-HSA-9674334] p-11Y PDGFRA D842L [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-9674313] p-11Y PDGFRA D842L dimer [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-1500709] PIK3CA E545G [cytosol]
[EntityWithAccessionedSequence:R-HSA-9660457] SHOC2 S2G [cytosol]
[Complex:R-HSA-9660488] S-GCC MRAS:GTP:SHOC2 S2G:PP1 [plasma membrane]
[Reaction:R-HSA-3215391] PRMT5 is tyrosine phosphorylated by JAK2 V617F
[ChemicalDrug:R-ALL-9679746] ponatinib [extracellular region]
[EntityWithAccessionedSequence:R-HSA-1838979] BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
[Complex:R-HSA-1838980] BCR-p-FGFR1 fusion mutant dimer [cytosol]
[CandidateSet:R-HSA-1839020] cytosolic p-FGFR1 fusion mutant dimers [cytosol]
[EntityWithAccessionedSequence:R-HSA-1839041] p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
[Complex:R-HSA-1839043] pY177-BCR-p-FGFR1 fusion mutant dimer [cytosol]
[EntityWithAccessionedSequence:R-HSA-1604524] BCR(1-584)-FGFR1(429-822) fusion [cytosol]
[Complex:R-HSA-1604525] BCR-FGFR1 fusion mutant dimer [cytosol]
[CandidateSet:R-HSA-1839026] cytosolic FGFR1 fusion mutant dimers [cytosol]
[CandidateSet:R-HSA-1839029] cytosolic FGFR1 fusion mutants [cytosol]
[Complex:R-HSA-1839047] pY177-BCR-pY-FGFR1 mutant:GRB2:p-GAB2 [cytosol]
[Complex:R-HSA-1839048] p-Y177-BCR-pY-FGFR1 mutant:GRB2:p-GAB2:PIK3R1 [cytosol]
[Complex:R-HSA-1839051] pY177-BCR-pY-FGFR1 mutant:GRB2:p-GAB1:PI3K [cytosol]
[Reaction:R-HSA-1839102] BCR-FGFR1 fusion:GRB2:p-GAB2:PIK3R1 binds PIK3CA
[Reaction:R-HSA-1839114] BCR-FGFR1:GRB2:p-GAB2 binds PIK3R1
[Complex:R-HSA-1839045] pY177-BCR1-p-FGFR1 mutant:GRB2:GAB2 [cytosol]
[Reaction:R-HSA-1839110] p-BCR-p-FGFR1 phosphorylates GAB2
[Reaction:R-HSA-1839095] p-BCR-pFGFR1 binds GRB2:GAB2
[Reaction:R-HSA-1839067] Phosphorylation of BCR moiety of BCR-FGFR1
[Complex:R-HSA-1839036] FGFR1 fusion mutant dimers:TKIs [cytosol]
[Reaction:R-HSA-1839039] Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation
[Reaction:R-HSA-1839107] BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3
[Pathway:R-HSA-1839117] Signaling by cytosolic FGFR1 fusion mutants
[EntityWithAccessionedSequence:R-HSA-5339682] GSK3B del304-316 [cytosol]
[Complex:R-HSA-5339714] p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol]
[Complex:R-HSA-5339712] pS45-beta-catenin:p-Axin:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol]
[FailedReaction:R-HSA-5339713] Misspliced GSK3beta mutants stabilize beta-catenin levels
[Pathway:R-HSA-5339716] Signaling by GSK3beta mutants
[EntityWithAccessionedSequence:R-HSA-9706197] CBL R420L [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706193] CBL R420P [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706642] CBL P417S [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706687] CBL Y371D [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706694] CBL Y371C [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706637] CBL H398P [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706638] CBL H398R [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706634] CBL P417L [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706630] CBL L380P [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706636] CBL P417A [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706639] CBL H398Y [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706680] CBL Y371H [cytosol]
[EntityWithAccessionedSequence:R-HSA-9706186] CBL R420Q [cytosol]
[EntityWithAccessionedSequence:R-HSA-9703317] SPTBN1(2-159)-p-6Y-FLT3(570-993) fusion [cytosol]
[Complex:R-HSA-9703376] SPTBN1(2-159)-p-6Y FLT3(570-993) fusion dimer [cytosol]
[EntityWithAccessionedSequence:R-HSA-9703316] SPTBN1(2-159)-FLT3(570-993) fusion [cytosol]
[Complex:R-HSA-9703361] SPTBN1(2-159)-FLT3570-993) fusion dimer [cytosol]

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