cubar: Codon Usage Bias Analysis

A suite of functions for rapid and flexible analysis of codon usage bias. It provides in-depth analysis at the codon level, including relative synonymous codon usage (RSCU), tRNA weight calculations, machine learning predictions for optimal or preferred codons, and visualization of codon-anticodon pairing. Additionally, it can calculate various gene- specific codon indices such as codon adaptation index (CAI), effective number of codons (ENC), fraction of optimal codons (Fop), tRNA adaptation index (tAI), mean codon stabilization coefficients (CSCg), and GC contents (GC/GC3s/GC4d). It also supports both standard and non-standard genetic code tables found in NCBI, as well as custom genetic code tables.

Version: 1.2.0
Depends: R (≥ 4.1.0)
Imports: Biostrings (≥ 2.60.0), IRanges (≥ 2.34.0), data.table (≥ 1.14.0), ggplot2 (≥ 3.3.5), rlang (≥ 0.4.11)
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0), reticulate
Published: 2025年08月19日
Author: Hong Zhang ORCID iD [aut, cre], Mengyue Liu [aut], Bu Zi [aut]
Maintainer: Hong Zhang <mt1022.dev at gmail.com>
License: MIT + file LICENSE
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: cubar results

Documentation:

Reference manual: cubar.html , cubar.pdf

Downloads:

Package source: cubar_1.2.0.tar.gz
Windows binaries: r-devel: cubar_1.2.0.zip, r-release: cubar_1.2.0.zip, r-oldrel: cubar_1.2.0.zip
macOS binaries: r-release (arm64): cubar_1.2.0.tgz, r-oldrel (arm64): cubar_1.2.0.tgz, r-release (x86_64): cubar_1.2.0.tgz, r-oldrel (x86_64): cubar_1.2.0.tgz
Old sources: cubar archive

Linking:

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