High-throughput analysis of growth curves and fluorescence
data using three methods: linear regression, growth model fitting, and
smooth spline fit. Analysis of dose-response relationships via
smoothing splines or dose-response models. Complete data analysis
workflows can be executed in a single step via user-friendly wrapper
functions. The results of these workflows are summarized in detailed
reports as well as intuitively navigable 'R' data containers. A 'shiny'
application provides access to all features without
requiring any programming knowledge. The package is described in further
detail in Wirth et al. (2023) <doi:10.1038/s41596-023-00850-7>.
Author:
Nicolas T. Wirth
ORCID iD
[aut, cre, cph],
Jonathan Funk [aut] (contribution: Co-developer of shiny app.),
Matthias Kahm [ctb] (contribution: Author of 'grofit' package, whose
general data structure was adopted for QurvE.),
Maik Kschischo [ctb] (contribution: Author of 'grofit' package, whose
general data structure was adopted for QurvE.),
Thomas Petzoldt
ORCID iD
[ctb] (contribution: Creator of the package 'growthrates', whose
function for calculating linear regressions served as a template in
QurvE.),
Andrew Stein [ctb] (contribution: Creator of 'xgxr' package from which
QurvE adopted code to plot axis ticks on log10 scale.),
Michael W. Kearney [ctb] (contribution: Creator of 'tfse' package from
which QurvE adopted the match_arg function.),
Santiago I. Hurtado [ctb] (contribution: Creator of 'RobustLinearReg'
package from which QurvE adopted the Theil Sehn Regression method.),
Mark Heckmann [ctb] (contribution: Creator of the 'zipFastener'
function; source:
https://ryouready.wordpress.com/2009/03/27/r-zip-fastener-for-two-data-frames-combining-rows-or-columns-of-two-dataframes-in-an-alternating-manner/),
Nicholas Hamilton [ctb] (contribution: Creator of the 'colFmt'
function.),
Evan Friedland [ctb] (contribution: Creator of the 'inflect' function.),
Heather Turner [ctb] (contribution: Creator of the 'base_breaks'
function.),
Georgi N. Boshnakov [ctb] (contribution: Creator of 'gbRd' package from
which functions are used to display function help pages within the
shiny app.)
Maintainer:
Nicolas T. Wirth <mail.nicowirth at gmail.com>