CRISPR Pooled Screen Analysis using Beta-Binomial Test [R package CB2 version 1.3.6]

Hyun-Hwan Jeong

CB2: CRISPR Pooled Screen Analysis using Beta-Binomial Test

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Version: 1.3.6

Depends: R (≥ 3.5.0)

Imports: Rcpp, metap, magrittr, dplyr, tibble, stringr, ggplot2, tidyr, glue, pheatmap, tools, readr, parallel, R.utils

LinkingTo: Rcpp, RcppArmadillo

Suggests: testthat, knitr, rmarkdown

Published: 2025年10月01日

DOI: 10.32614/CRAN.package.CB2

Author: Hyun-Hwan Jeong [aut, cre]

Maintainer: Hyun-Hwan Jeong <hyunhwanjeong at icloud.com>

License: MIT + file LICENSE

NeedsCompilation: yes

Materials: README

In views: Omics

CRAN checks: CB2 results

Documentation:

Reference manual: CB2.html , CB2.pdf

Vignettes: Handling the input matrix in CB2 (source, R code)
CB2 Tutorial (source, R code)

Downloads:

Package source: CB2_1.3.6.tar.gz

Windows binaries: r-devel: CB2_1.3.6.zip, r-release: CB2_1.3.6.zip, r-oldrel: CB2_1.3.6.zip

macOS binaries: r-release (arm64): CB2_1.3.6.tgz, r-oldrel (arm64): CB2_1.3.6.tgz, r-release (x86_64): CB2_1.3.6.tgz, r-oldrel (x86_64): CB2_1.3.6.tgz

Old sources: CB2 archive

Linking:

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