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chipseqDB

This is the released version of chipseqDB; for the devel version, see chipseqDB.

A Bioconductor Workflow to Detect Differential Binding in ChIP-seq Data


Bioconductor version: Release (3.22)

Describes a computational workflow for performing a DB analysis with sliding windows. The aim is to facilitate the practical implementation of window-based DB analyses by providing detailed code and expected output. The workflow described here applies to any ChIP-seq experiment with multiple experimental conditions and multiple biological samples in one or more of the conditions. It detects and summarizes DB regions between conditions in a de novo manner, i.e., without making any prior assumptions about the location or width of bound regions. Detected regions are then annotated according to their proximity to genes.

Author: Aaron Lun [aut, cre], Gordon Smyth [aut]

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>

Citation (from within R, enter citation("chipseqDB")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("chipseqDB")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("chipseqDB")
1. Introduction HTML
2. Differential enrichment of H3K9ac in B cells HTML
3. Differential binding of CBP in fibroblasts HTML R Script
4. Differential enrichment of H3K27me3 in lung epithelium HTML

Details

Version 1.34.0
License Artistic-2.0
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package chipseqDB_1.34.0.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/chipseqDB
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/chipseqDB
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