Prof. Ada E. Yonath Group
Ribosome structure and function,
human genetic diseases linked to mutated ribosomes,
next generation antibiotics & origin of life
The Martin
S. and Helen Kimmel Professor of Structural Biology
Director, The Helen and Milton A. Kimmelman
Center for Biomolecular Structure and Assembly
NOBEL
PRIZE IN CHEMISTRY 2009
Tel:
(972) 8 934 3028/2541;
Fax: (972) 8 934 4154/4136
Ribosome Group led by Prof Ada
Yonath:
Chemical and Structural Biology Department, Weizmann Institute of Science, Rehovot, Israel
Members of the group:
Admon Roni*, Dr. Agmon Ilana*, Assis Nofar*, Dr. Auerbach-Nevo Tamar*,
Dr. Baram David*, Dr. Bashan Anat, Dr. Belousoff Matthew*, Dr. Bose Tanaya,
Dr. Breiner Elinor*, Dr. Cimicata Giuseppe, Dr. Davidovich Chen*, Dr. Eyal Zohar*, Fedorenko Aliza, Dr. Franklin John, Dr.
Fridkin Gil, Dr. Halfon Yehuda*, Hiregange Disha-Gajanan, Dr. Pyetan Erez*, Kaczmarczyk Igor*, Dr. Kessler
Maggie, Dr. Krupkin Miri*, Laschever Miriam*, Dr. Matzov Donna*, Melenitzki Tal, Metz Markus*, Dr.
Mruwat Rufayda*, Dr. Peretz Moshe, Rivalta Andre', Rosenfield Liat, Dr. Rozenberg Haim, Saha Chiranjeet, Samiya Sarit*, Dr. Shalev-Benami
Moran*, Dr. Shanmugha Rajan K, Shapira Tal*, Dr. Sun Liping*, Tel-Or Shoshi, Waghalter Miriam, Dr. Wekselman Itai*, Dr. Zarivach Raz*,
Dr. Zimmerman Ella
* Previous Members
Scientific Activities and explanation
to the below Figures
Publications
Ada E.Yonath Curriculum Vitae
Ada E.Yonath Curriculum Vitae (Heb)
[画像:Schluenzen et al., Cell, 102, 615-23 (2000)]
Figure A:
The Small Ribosomal Subunit
[画像:Harms et al., Cell, 107, 679-88 (2001)]
Figure B:
The Large Ribosomal Subunit
[画像:Agmon etal., Eur J Biochem, 270, 2543-56(2003); Bashan et al., Mol Cell, 11,91-102 (2003); Yonath, ChemBioChem 4, 1008-17 (2003); Yonath, Biol Chem 384, 1411-9 (2003)]
*Figure C:
tRNA A-site --->P site
[画像:Agmon et al., Eur J Biochem, 270, 2543-56 (2003); Bashan et al., Mol Cell, 11,91-102 (2003) ]
*Figure D:
tRNA A-site--->P passage
[画像:View into the Tunnel]
Figure E:View into the Tunnel
Schluenzen et al., Nature, 413, 814-21 (2001)
Wekselman et al., Structure 25, 1233-1241 (2017)
[画像:Schluenzen et al., Nature, 413, 814-21 (2001)]
Figure F:Antibiotic Agents Blocking the Ribosmal Exit Tunnel
[画像:NEXT GENERATION ENVIRONMENTAL FRIENDLY ANTIBIOTICS]
Figure G:
Next Generation Environmental
Friendly Antibiotics
Ribosome in action (Eng):
http://www.youtube.com/watch?v=Jml8CFBWcDs
Ribosome in action (Chinese):
http://v.youku.com/v_show/id_XNzMxNzEwNjg0.html
Antibiotics targeting ribosomes (Eng):
http://www.youtube.com/watch?v=RedO6rLNQ2o
Antibiotics targeting ribosomes (Chinese):
http://v.youku.com/v_show/id_XNzMyNDU4Mzgw.html
Scientific Activities and explanation to the below Figures
Publications
Ada E.Yonath Curriculum Vitae
Ada E.Yonath Curriculum Vitae (Heb)
