The Glycolytic Cycle

illustrated by L. Van Warren

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Mg²⁺

DG¹⁰= -4.0 kcal/mol

D-glucose-6-phosphate

Mg²⁺

or

Mn²⁺

phosphoglucoisomerase

DG¹⁰= 0.4 kcal/mol

D-fructose-6-phosphate

Mg²⁺

phosphofructokinase

(6-phosphofructo-2-kinase shown)

DG¹⁰= -4.0 kcal/mol

D-fructose-1,6-diphosphate

DG¹⁰= 5.73 kcal/mol

dihydroxyacetone

DG¹⁰= 1.83 kcal/mol

glyceraldehyde-3-phosphate

trisephophate isomerase

glyceraldehyde-3-P dehydrogenase

NADH + H⁺

NAD⁺, Phosphate

DG¹⁰= 1.5 kcal/mol

1,3-diphosphoglycerate

Mg²⁺

phosphoglycerate kinase

DG¹⁰= -4.5 kcal/mol

3-phosphoglycerate

Mg²⁺

phosphoglycerate mutase

DG¹⁰= 1.06 kcal/mol

2-phosphoglycerate

Mg²⁺

or

Mn²⁺

DG¹⁰= 0.44 kcal/mol

2-phosphoenolpyruvate

Mg²⁺

and

K⁺

pyruvate kinase

DG¹⁰= -7.5 kcal/mol

lactate dehydrogenase

NADH + H⁺

NAD⁺

DG¹⁰= -6.0 kcal/mol

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Pathway Animation Copyright 1998:

L. Van Warren

Warren Design Vision

All Rights Reserved

* - adapted from:

Organic Chemistry

by

Paula Yurkanis Bruice