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. 2023 Aug 1;50(8):490-493.
doi: 10.1097/OLQ.0000000000001810. Epub 2023 Mar 23.

Doxycycline Postexposure Prophylaxis Could Induce Cross-Resistance to Other Classes of Antimicrobials in Neisseria gonorrhoeae : An In Silico Analysis

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Doxycycline Postexposure Prophylaxis Could Induce Cross-Resistance to Other Classes of Antimicrobials in Neisseria gonorrhoeae : An In Silico Analysis

Thibaut Vanbaelen et al. Sex Transm Dis. .

Abstract

We found that tetracycline resistance-associated mutations and genes in Neisseria gonorrhoeae are linked to mutations causing resistance to other antimicrobials. Therefore, the use of doxycycline postexposure prophylaxis may select for resistance to other antimicrobials.

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Conflict of interest statement

Conflict of Interest and Sources of Funding: None declared.

References

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