Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
NC3Rs staff have co-authored a new chapter in the IACUC Handbook to support ethical review bodies in assessing the reliability of animal research.
Report highlights the outcomes of the first UK funding call for infrastructure to support animal replacement methods, delivered by the NC3Rs.
Our annual summer school supports early career researchers in their role as ambassadors for the 3Rs, throughout their PhD and beyond.
Joint report from the NC3Rs, ABPI and MHRA, exploring how New Approach Methodologies can transform the way medicines are developed.
Research recognised by this years’ International 3Rs Prize focuses on strengthening the evidence base to build confidence in and drive uptake of replacement technologies.
The NC3Rs has committed over 60ドルM for research and innovation to develop human-based in vitro models that replace the use of animals, better recapitulate human physiology and disease and increase the efficiency of drug development.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
