Cd24a MGI Mouse Gene Detail - MGI:88323 - CD24a antigen

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Cd24a Gene Detail
Summary
  • Symbol
    Cd24a
  • Name
    CD24a antigen
  • Synonyms
    cluster of differentiation 24, heat stable antigen, HSA, Ly-52, nectadrin
  • Feature Type
    protein coding gene
  • IDs
    MGI:88323
    NCBI Gene: 12484
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:43454433-43460261 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 23.01 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    16
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88323
protein coding gene Chr10:43454280-43460261 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017195
protein coding gene Chr10:42363170-42368264 (+)
A/J MGP_AJ_G0017173
protein coding gene Chr10:41182841-41188155 (+)
AKR/J MGP_AKRJ_G0017133
protein coding gene Chr10:41799972-41805085 (+)
BALB/cJ MGP_BALBcJ_G0017134
protein coding gene Chr10:41222973-41228060 (+)
C3H/HeJ MGP_C3HHeJ_G0016955
protein coding gene Chr10:42151967-42157064 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017594
protein coding gene Chr10:43669584-43674675 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015289
protein coding gene Chr10:39125446-39130863 (+)
CAST/EiJ MGP_CASTEiJ_G0016534
protein coding gene Chr10:42380765-42386210 (+)
CBA/J MGP_CBAJ_G0016929
protein coding gene Chr10:45646644-45651735 (+)
DBA/2J MGP_DBA2J_G0017035
protein coding gene Chr10:40638514-40643591 (+)
FVB/NJ MGP_FVBNJ_G0017030
protein coding gene Chr10:40133892-40138985 (+)
LP/J MGP_LPJ_G0017111
protein coding gene Chr10:42377497-42382812 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017059
protein coding gene Chr10:46361181-46368900 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0016098
protein coding gene Chr10:41653543-41658424 (+)
WSB/EiJ MGP_WSBEiJ_G0016597
protein coding gene Chr10:42089307-42094386 (+)



Homology
more
  • Human Ortholog
    CD24, CD24 molecule
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD24, CD24 molecule
  • Synonyms
    CD24A
  • Links
    NCBI Gene ID: 100133941
    UniProt: P25063

  • Chr Location
    chr6:106969831-106976855 (-) GRCh38
Human Diseases
more
  • Diseases
    1 with human CD24 associations

Human Disease Mouse Models
IDs
multiple sclerosis

DOID:2377
ICD10CM:G35
ICD9CM:340
MESH:D009103
NCI:C3243
OMIM:612594
OMIM:612595
OMIM:612596
UMLS_CUI:C0026769
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    49 phenotype references
Phenotype Overview

Phenotype Overview
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.
adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in slight impairment of B cell development. Mutant erythrocytes have increased tendency to aggregate.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

Expression Overview
GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.
  • Blue cells = expressed in wild-type.
    Gray triangles = other expression annotations only
    (e.g. absence of expression or data from mutants).
early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12484 NCBI Gene Model | MGI Sequence Detail 5829 C57BL/6J ± kb
    transcript NM_001428380 RefSeq | MGI Sequence Detail 1884 C57BL/6
    polypeptide P24807 UniProt | EBI | MGI Sequence Detail 76 Not Applicable
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 469
      Genomic 2
      cDNA 462
      Primer pair 3
      Other 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-11995, MGD-MRK-1840
    References
    more
    • Summaries
      All 185
      Developmental Gene Expression 40
      Gene Ontology 69
      Phenotypes 49
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:365097 Shihan MH, et al., CD24 is required for sustained transparency of the adult lens. Exp Eye Res. 2025 Mar 18;255:110347
    TSS for Cd24a:
    (View these features in JBrowse)
    Transcription Start Site Location Distance from Gene 5'-end
    Tssr93141 Chr10:43455157-43455174 (+) 733 bp
    Tssr93142 Chr10:43455919-43455941 (+) 1,497 bp
    Tssr93143 Chr10:43458685-43458727 (+) 4,273 bp
    Tssr93144 Chr10:43459892-43459896 (+) 5,461 bp
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support. last database update
    10/07/2025
    MGI 6.24 The Jackson Laboratory
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