Ccdc166 MGI Mouse Gene Detail - MGI:1925902 - coiled-coil domain containing 166

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Ccdc166 Gene Detail
Summary
  • Symbol
    Ccdc166
  • Name
    coiled-coil domain containing 166
  • Synonyms
    2410075B13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925902
    NCBI Gene: 223648
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75851721-75854134 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.18 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925902
protein coding gene Chr15:75851721-75854304 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021969
protein coding gene Chr15:76032131-76034714 (-)
A/J MGP_AJ_G0021927
protein coding gene Chr15:73262303-73264886 (-)
AKR/J MGP_AKRJ_G0021910
protein coding gene Chr15:75244494-75247077 (-)
BALB/cJ MGP_BALBcJ_G0021936
protein coding gene Chr15:73282423-73285006 (-)
C3H/HeJ MGP_C3HHeJ_G0021708
protein coding gene Chr15:75301062-75303645 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022376
protein coding gene Chr15:78869926-78872509 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0021227
protein coding gene Chr15:76089228-76091811 (-)
CBA/J MGP_CBAJ_G0021675
protein coding gene Chr15:81381389-81383972 (-)
DBA/2J MGP_DBA2J_G0021800
protein coding gene Chr15:72792850-72795433 (-)
FVB/NJ MGP_FVBNJ_G0021781
protein coding gene Chr15:71843322-71845905 (-)
LP/J MGP_LPJ_G0021871
protein coding gene Chr15:76111298-76113881 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021805
protein coding gene Chr15:86684434-86687017 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022396
protein coding gene Chr15:75492182-75494765 (-)
PWK/PhJ MGP_PWKPhJ_G0020968
protein coding gene Chr15:72935798-72938380 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020807
protein coding gene Chr15:75210132-75212708 (-)
WSB/EiJ MGP_WSBEiJ_G0021279
protein coding gene Chr15:75575115-75577698 (-)



Homology
more
  • Human Ortholog
    CCDC166, coiled-coil domain containing 166
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC166, coiled-coil domain containing 166
  • Links
    NCBI Gene ID: 100130274
    UniProt: P0CW27

  • Chr Location
    8q24.3; chr8:143706694-143708109 (-) GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

Phenotype Overview
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.
adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    2
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Ccdc166
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

Expression Overview
GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.
  • Blue cells = expressed in wild-type.
    Gray triangles = other expression annotations only
    (e.g. absence of expression or data from mutants).
early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
    2
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 223648 NCBI Gene Model | MGI Sequence Detail 2414 C57BL/6J ± kb
transcript NM_001163518 RefSeq | MGI Sequence Detail 2414 C57BL/6
polypeptide NP_666171 RefSeq | MGI Sequence Detail 449 C57BL/6
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR032777 Domain of unknown function DUF4515
  • GlyGen
    S4R181 1 site
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 5
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
TSS for Ccdc166:
(View these features in JBrowse)
Transcription Start Site Location Distance from Gene 5'-end
Tssr134892 Chr15:75853793-75853849 (-) 313 bp
Tssr134891 Chr15:75853672-75853687 (-) 454 bp
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. last database update
10/07/2025
MGI 6.24 The Jackson Laboratory
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