Alg3 MGI Mouse Gene Detail - MGI:1098592 - ALG3 alpha-1,3- mannosyltransferase

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Alg3 Gene Detail
Summary
  • Symbol
    Alg3
  • Name
    ALG3 alpha-1,3- mannosyltransferase
  • Synonyms
    D16Ertd36e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098592
    NCBI Gene: 208624
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:20424208-20429515 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 12.48 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098592
protein coding gene Chr16:20424124-20430485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022647
protein coding gene Chr16:17942874-17948191 (-)
A/J MGP_AJ_G0022609
protein coding gene Chr16:17079932-17085246 (-)
AKR/J MGP_AKRJ_G0022584
protein coding gene Chr16:17726588-17731905 (-)
BALB/cJ MGP_BALBcJ_G0022613
protein coding gene Chr16:17237599-17242916 (-)
C3H/HeJ MGP_C3HHeJ_G0022378
protein coding gene Chr16:17892828-17898145 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023064
protein coding gene Chr16:18290183-18295500 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020581
protein coding gene Chr16:17765534-17770857 (-)
CAST/EiJ MGP_CASTEiJ_G0021908
protein coding gene Chr16:17866942-17872251 (-)
CBA/J MGP_CBAJ_G0022350
protein coding gene Chr16:19043183-19048500 (-)
DBA/2J MGP_DBA2J_G0022482
protein coding gene Chr16:17006222-17011539 (-)
FVB/NJ MGP_FVBNJ_G0022457
protein coding gene Chr16:17041723-17047040 (-)
LP/J MGP_LPJ_G0022549
protein coding gene Chr16:17674696-17680013 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022477
protein coding gene Chr16:18723403-18728720 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023075
protein coding gene Chr16:17691864-17697181 (-)
PWK/PhJ MGP_PWKPhJ_G0021649
protein coding gene Chr16:17268775-17274569 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021478
protein coding gene Chr16:17489450-17495533 (-)
WSB/EiJ MGP_WSBEiJ_G0021952
protein coding gene Chr16:17682585-17691121 (-)



Homology
more
  • Human Ortholog
    ALG3, ALG3 alpha-1,3- mannosyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALG3, ALG3 alpha-1,3- mannosyltransferase
  • Synonyms
    CDG1D, CDGS4, CDGS6, D16Ertd36e, not, Not56, NOT56L
  • Links
    NCBI Gene ID: 10195
    UniProt: Q92685

  • Chr Location
    3q27.1; chr3:184242301-184249548 (-) GRCh38
Human Diseases
more
  • Diseases
    1 with human ALG3 associations

Human Disease Mouse Models
IDs
congenital disorder of glycosylation Id
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

Phenotype Overview
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.
adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

Expression Overview
GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.
  • Blue cells = expressed in wild-type.
    Gray triangles = other expression annotations only
    (e.g. absence of expression or data from mutants).
early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 208624 NCBI Gene Model | MGI Sequence Detail 5308 C57BL/6J ± kb
transcript NM_145939 RefSeq | MGI Sequence Detail 1437 ZRU/MplStud
polypeptide Q8K2A8 UniProt | EBI | MGI Sequence Detail 438 Not Applicable
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 7
  • Earliest
    J:50320 Pappano WN, et al., Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes. Genomics. 1998 Sep 1;52(2):236-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
TSS for Alg3:
(View these features in JBrowse)
Transcription Start Site Location Distance from Gene 5'-end
Tssr140390 Chr16:20429491-20429507 (-) 16 bp
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. last database update
10/07/2025
MGI 6.24 The Jackson Laboratory
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