[フレーム]
Home Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan
Article
Licensed
Unlicensed Requires Authentication

Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan

  • Fujio Kayama EMAIL logo , Zafar Fatmi , Akihiko Ikegami , Atsuko Mizuno , Mayumi Ohtsu , Nathern Mise , Xiaoyi Cui , Masanori Ogawa , Takako Sakamoto , Yoshiko Nakagi , Takahiko Yoshida , Ambreen Sahito , Shahla Naeem , Kulsoom Ghias , Hina Zuberi , Kanwal Tariq , Yayoi Kobayashi and Keiko Nohara
Published/Copyright: March 8, 2016

Abstract

Aim: Exposure assessment of lead (Pb) and Arsenic (As) from food, water, and house dust intake were assessed among pregnant women, their children and fetuses in Pakistan and Japan, as well as their body burden of the metals in their blood.

Method: Fifty families which included a pregnant woman, a fetus and the 1–3-year-old siblings were recruited in Karachi and Khairpur in Pakistan, and Shimotsuke and Asahikawa in Japan, respectively. Their dietary exposure to Pb and As was measured in 3-day food duplicates and drinking water by ICP-MP. Pb in house dust and respirable dust was evaluated with an energy dispersive X-ray fluorescence spectrometry. Non-radioactive isotope Pb profiles of blood specimens will be compared with those of the exposure origins, such as food duplicates, respirable house dust, the soils nearby, and gasoline.

Results: Judging from the data collected and analyzed so far, contribution from dietary intake is highly correlated to higher body burden of Pb among Pakistani mothers. Additional data analyses will reveal the status of Pb and As body burden in Pakistani mothers, fetuses and their siblings, and causal sources of high body burden is delineated by Pb isotope profile analysis of different sources of Pb exposure.

Corresponding author: Fujio Kayama, Department of Environmental and Preventive Medicine, Jichi Medical University, Shimono, Tochigi, Japan, E-mail: kayamaf@jichi.ac.jp

References

1. Lanphear BP, Hornung R, Khoury J, Yolton K, Baghurst P, et al. Low-level environmental lead exposure and children’s intellectual function: an international pooled analysis. Environ Health Perspect 2005;113(7):894–9.10.1289/ehp.7688 Search in Google Scholar PubMed PubMed Central

2. Bellinger DC. What is an adverse effect? A possible resolution of clinical and epidemiological perspectives on neurobehavioral toxicity. Environ Res 2004;95:394–405.10.1016/j.envres.2003年07月01日3 Search in Google Scholar PubMed

3. Domingo JL, Perelló G, Giné Bordonaba J. Dietary intake of metals by the population of tarragona county (Catalonia, Spain): results from a duplicate diet study. Biol Trace Elem Res 2012;146(3):420–5.10.1007/s12011-011-9269-5 Search in Google Scholar PubMed

4. Lanphear BP, Hornung R, Ho M, Howard CR, Eberly S, et al. Environmental lead exposure during early childhood. J Pediatr 2002;140(1):40–7.10.1067/mpd.2002.120513 Search in Google Scholar PubMed

5. Kapaj S, Peterson H, Liber K, Bhattacharya P. Human health effects from chronic arsenic poisoning – A review. J Environ Sci Health A Tox Hazard Subst Environ Eng 2006;41(10):2399–428.10.1080/10934520600873571 Search in Google Scholar PubMed

6. Schuhmacher-Wolz U, Dieter HH, Klein D, Schneider K. Oral exposure to inorganic arsenic: evaluation of its carcinogenic and non-carcinogenic effects. Crit Rev Toxicol 2009;39(4):271–98.10.1080/10408440802291505 Search in Google Scholar PubMed

7. Kadir MM, Janjua NZ, Kristensen S, Fatmi Z, Sathiakumar N. Status of children’s blood lead levels in Pakistan: implications for research and policy. Public Health 2008;122(7):708–15.10.1016/j.puhe.2007年08月01日2 Search in Google Scholar PubMed PubMed Central

8. Iqbal MP. Lead pollution – A risk factor for cardiovascular disease in Asian developing countries. Pak J Pharm Sci 2012;25(1):289–94.Search in Google Scholar

9. Fatmi Z, Abbasi IN, Ahmed M, Kazi A, Kayama F. Burden of skin lesions of arsenicosis at higher exposure through groundwater of taluka Gambat district Khairpur, Pakistan: a cross-sectional survey. Environ Geochem Health 2013;35(3):341–6.10.1007/s10653-012-9498-3 Search in Google Scholar PubMed

10. Hedrick VE, Dietrich AM, Estabrooks PA, Savla J, Serrano E, et al. Dietary biomarkers: advances, limitations and future directions. Nutr J 2012;11:109–12.10.1186/1475-2891年11月10日9 Search in Google Scholar PubMed PubMed Central

11. Schecter A, Päpke O, Harris TR, Tung KC, Musumba A, et al. Polybrominated diphenyl ether (PBDE) levels in an expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex. Environ Health Perspect 2006;114(10):1515–20.10.1289/ehp.9121 Search in Google Scholar PubMed PubMed Central

12. Zahir E, Naqvi IM, Mohi Uddin S. Market basket survey of selected metals in fruits from Karachi city (Pakistan). J Basic Appl Sci 2009;5(2):47–52.Search in Google Scholar

13. Rahbar MH, White F, Agboatwalla M, Hozhabri S, Luby S. Factors associated with elevated blood lead concentrations in children in Karachi, Pakistan. Bull World Health Organ 2002;80:769–75.Search in Google Scholar

Received: 2015年10月14日
Accepted: 2015年10月14日
Published Online: 2016年03月08日
Published in Print: 2016年03月01日

©2016 by De Gruyter

You are currently not able to access this content.
You are currently not able to access this content.

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Traditional and emerging environmental hazards in South-East Asia: double-trouble in the 21st century
  4. A quarter century of the Pacific Basin Consortium: looking back to move forward
  5. Exposure to Metals
  6. Arsenic projects in SE Asia
  7. Lead exposure from battery recycling in Indonesia
  8. Connecting mercury science to policy: from sources to seafood
  9. Mercury exposure in the work place and human health: dental amalgam use in dentistry at dental teaching institutions and private dental clinics in selected cities of Pakistan
  10. Protecting health from metal exposures in drinking water
  11. Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan
  12. Mining
  13. Reconciling PM10 analyses by different sampling methods for Iron King Mine tailings dust
  14. The "CHILD" framework for the study of artisanal mercury mining communities
  15. Hydraulic fracturing for natural gas: impact on health and environment
  16. Hazardous Waste
  17. Searching bioremediation patents through Cooperative Patent Classification (CPC)
  18. Proteomics of Sphingobium indicum B90A for a deeper understanding of hexachlorocyclohexane (HCH) bioremediation
  19. Novel industrial wastewater treatment integrated with recovery of water and salt under a zero liquid discharge concept
  20. Water
  21. Connecting science with industry: lessons learned transferring a novel plasmonic mercury sensor from the bench to the field
  22. Pilot-scale UV/H2O2 study for emerging organic contaminants decomposition
  23. Nanotechnology: a clean and sustainable technology for the degradation of pharmaceuticals present in water and wastewater
  24. Solar-driven membrane distillation demonstration in Leupp, Arizona
  25. What works in water supply and sanitation projects in developing countries with EWB-USA
  26. Natural Disasters and a Changing Environment
  27. Environmental exposures due to natural disasters
  28. Changing exposures in a changing world: models for reducing the burden of disease
  29. Sustainable development through a gendered lens: climate change adaptation and disaster risk reduction
  30. Environmental Justice and Human Rights
  31. Creating healthy and just bioregions
  32. Worm-free children: an integrated approach to reduction of soil-transmitted helminth infections in Central Java
  33. Diabetes in Native Americans: elevated risk as a result of exposure to polychlorinated biphenyls (PCBs)
  34. Pollution, health and development: the need for a new paradigm
  35. EcoSystem
  36. Pacific connections for health, ecosystems and society: new approaches to the land-water-health nexus
  37. Exposure to e-waste
  38. E-waste: the growing global problem and next steps
  39. Global challenges for e-waste management: the societal implications
  40. E-waste issues in Sri Lanka and the Basel Convention
  41. E-waste interventions in Ghana
  42. CALUX bioassay: a cost-effective rapid screening technique for screening dioxins like compounds
  43. Cancer
  44. Cancer surveillance and research on environmental contributions to cancer
  45. Domestic incense use and lung cancer in Asia: a review
  46. Children
  47. Inadequate water, sanitation and hygiene in the South Pacific: how might it be impacting children?
  48. Children’s environmental health indicators in Australia: are we collecting the right information?
  49. Community-based efforts in health promotion in indigenous villages on the Thailand-Myanmar border
  50. Emerging issues
  51. Bayesian networks in infectious disease eco-epidemiology
  52. Health co-benefits in mortality avoidance from implementation of the mass rapid transit (MRT) system in Kuala Lumpur, Malaysia
  53. Particulate matter 2.5 (PM2.5) personal exposure evaluation on mechanics and administrative officers at the motor vehicle testing center at Pulo Gadung, DKI Jakarta
  54. Life cycle assessment of dairy farms
Search journal

Articles in the same Issue

  1. Frontmatter
  2. Editorial
  3. Traditional and emerging environmental hazards in South-East Asia: double-trouble in the 21st century
  4. A quarter century of the Pacific Basin Consortium: looking back to move forward
  5. Exposure to Metals
  6. Arsenic projects in SE Asia
  7. Lead exposure from battery recycling in Indonesia
  8. Connecting mercury science to policy: from sources to seafood
  9. Mercury exposure in the work place and human health: dental amalgam use in dentistry at dental teaching institutions and private dental clinics in selected cities of Pakistan
  10. Protecting health from metal exposures in drinking water
  11. Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan
  12. Mining
  13. Reconciling PM10 analyses by different sampling methods for Iron King Mine tailings dust
  14. The "CHILD" framework for the study of artisanal mercury mining communities
  15. Hydraulic fracturing for natural gas: impact on health and environment
  16. Hazardous Waste
  17. Searching bioremediation patents through Cooperative Patent Classification (CPC)
  18. Proteomics of Sphingobium indicum B90A for a deeper understanding of hexachlorocyclohexane (HCH) bioremediation
  19. Novel industrial wastewater treatment integrated with recovery of water and salt under a zero liquid discharge concept
  20. Water
  21. Connecting science with industry: lessons learned transferring a novel plasmonic mercury sensor from the bench to the field
  22. Pilot-scale UV/H2O2 study for emerging organic contaminants decomposition
  23. Nanotechnology: a clean and sustainable technology for the degradation of pharmaceuticals present in water and wastewater
  24. Solar-driven membrane distillation demonstration in Leupp, Arizona
  25. What works in water supply and sanitation projects in developing countries with EWB-USA
  26. Natural Disasters and a Changing Environment
  27. Environmental exposures due to natural disasters
  28. Changing exposures in a changing world: models for reducing the burden of disease
  29. Sustainable development through a gendered lens: climate change adaptation and disaster risk reduction
  30. Environmental Justice and Human Rights
  31. Creating healthy and just bioregions
  32. Worm-free children: an integrated approach to reduction of soil-transmitted helminth infections in Central Java
  33. Diabetes in Native Americans: elevated risk as a result of exposure to polychlorinated biphenyls (PCBs)
  34. Pollution, health and development: the need for a new paradigm
  35. EcoSystem
  36. Pacific connections for health, ecosystems and society: new approaches to the land-water-health nexus
  37. Exposure to e-waste
  38. E-waste: the growing global problem and next steps
  39. Global challenges for e-waste management: the societal implications
  40. E-waste issues in Sri Lanka and the Basel Convention
  41. E-waste interventions in Ghana
  42. CALUX bioassay: a cost-effective rapid screening technique for screening dioxins like compounds
  43. Cancer
  44. Cancer surveillance and research on environmental contributions to cancer
  45. Domestic incense use and lung cancer in Asia: a review
  46. Children
  47. Inadequate water, sanitation and hygiene in the South Pacific: how might it be impacting children?
  48. Children’s environmental health indicators in Australia: are we collecting the right information?
  49. Community-based efforts in health promotion in indigenous villages on the Thailand-Myanmar border
  50. Emerging issues
  51. Bayesian networks in infectious disease eco-epidemiology
  52. Health co-benefits in mortality avoidance from implementation of the mass rapid transit (MRT) system in Kuala Lumpur, Malaysia
  53. Particulate matter 2.5 (PM2.5) personal exposure evaluation on mechanics and administrative officers at the motor vehicle testing center at Pulo Gadung, DKI Jakarta
  54. Life cycle assessment of dairy farms
Sign up now to receive a 20% welcome discount
Subscribe to our newsletter
Institutional Access
How does access work?
Have an idea on how to improve our website?
Please write us.
© 2025 De Gruyter Brill
Downloaded on 23.10.2025 from https://www.degruyterbrill.com/document/doi/10.1515/reveh-2015-0046/html

AltStyle によって変換されたページ (->オリジナル) /