Human granulocytotropic anaplasmosis—A systematic review and analysis of the literature

Rocky Mountain spotted fever (RMSF), a severe and extraordinarily lethal infectious disease, has emerged as a widespread public health crisis among predominantly vulnerable populations in several countries of Latin America, particularly evident in northern Mexico. Historically, RMSF has gained less attention than many other tropical infectious diseases, resulting in insufficient allocations of resources and development of...

The WHO has successfully controlled lymphatic filariasis and onchocerciasis transmission with mass drug administration (MDA) in almost all the areas it has targeted. The success of Latin American filarial disease control programs means the region will soon be free of both onchocerciasis and lymphatic filariasis; however, the elimination of these diseases in Africa and the control and elimination of other filarial diseases, like loiasis and mansonellosis, will require blood surveys in regions with little or no base-line surveillance data. Historical...

The risk of severe malaria from the zoonotic parasite Plasmodium knowlesi approximates that from P. falciparum. In severe falciparum malaria, neutrophil activation contributes to inflammatory pathogenesis, including acute lung injury. The role of neutrophil activation in the pathogenesis of severe knowlesi malaria has not been examined. We evaluated 213 patients with P. knowlesi mono-infection (138 non-severe, 75...