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Open Access
Peer-reviewed
Research Article
Homeostatic bidirectional plasticity in upbound and downbound micromodules in a model of the olivocerebellar loop
Homeostatic bidirectional plasticity in upbound and downbound micromodules in a model of the olivocerebellar loop
- Elías M. Fernández Santoro,
- Lennart P.L. Landsmeer,
- Said Hamdioui,
- Christos Strydis,
- Chris I. De Zeeuw,
- Aleksandra Badura,
- Mario Negrello
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- Published: October 21, 2025
- https://doi.org/10.1371/journal.pcbi.1013609
About the Authors
- Elías M. Fernández Santoro
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Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
- Lennart P.L. Landsmeer
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Roles Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands, Quantum & Computer Engineering Department, Delft University of Technology, Delft, The Netherlands
- Said Hamdioui
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Roles Funding acquisition, Writing – review & editing
Affiliation Quantum & Computer Engineering Department, Delft University of Technology, Delft, The Netherlands
- Christos Strydis
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Roles Funding acquisition, Writing – review & editing
Affiliations Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands, Quantum & Computer Engineering Department, Delft University of Technology, Delft, The Netherlands
- Chris I. De Zeeuw
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Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands, Netherlands Institute for Neuroscience, Royal Academy of Arts and Sciences, Amsterdam, The Netherlands
- Aleksandra Badura
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Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: m.negrello@erasmusmc.nl (MN); a.badura@erasmusmc.nl (AB)
Affiliation Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
- Mario Negrello
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Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: m.negrello@erasmusmc.nl (MN); a.badura@erasmusmc.nl (AB)
Affiliations Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands, Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, The Netherlands
Competing Interests
The authors have declared that no competing interests exist.