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Have you taken a look at "Nurbits"? #13

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Description

Nurbits is new music puzzler based on real neuroscience. It launches July 17th on Steam. The dev team is funded by the National Institutes of Health (specifically NIMH) and they've been doing educational r&d for the past 2 years. The game has been shown to teach college level neuroscience concepts to middle schoolers!

From its description:

You take on the role of a sound engineer responsible for producing music with a robot band. You must fix the wiring in each robot's brain before it can play the song.

To do so, you hook up computer chips that send and receive signals the same way that neurons do. Each chip has a threshold. If it receives enough stimulation from other chips to reach threshold it will fire and play a note. To solve the puzzle you must hook up the right notes and inhibit the wrong notes. Each puzzle is a phrase in the song the player is assembling. Complete all the puzzles so the band can play the song!

So what do you think? Is it worth adding to the list?

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