It actually works pretty great! I put together a very simple PyQt6 app here and then used the following steps with pyapp:

• Download the latest version as described in the how-to
• Create a requirements.txt pointing at pip installation from git, e.g., via

  echo 'git+https://github.com/trappitsch/qtcowsay' > requirements.txt

• Set the following environment variables

  Option	Value
  PYAPP_PROJECT_NAME	qtcowsay
  PYAPP_PROJECT_VERSION	0.0.2
  PYAPP_PROJECT_DEPENDENCY_FILE	./requirements.txt
  PYAPP_EXEC_SPEC	qtcowsay:run

Then simply cargo build --release and the GUI should start.

Just my first test, still experimenting with local setup, isolation, and some nicer entry into the module... (the __init__.py is currently kind of ugly and just runs the app upon import...).

Hope this helps!

Updated: see comment below