initiation codon


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initiation codon

[i‚nish·ē′ā·shən ′kō‚dän]
(genetics)
A codon that signals the first amino acid in a protein sequence; usually AUG, but sometimes GUG. Also known as start codon.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production.
In EBS, KLHL24 mutation affect methionine initiation codons, resulting in the loss of the first 28 amino acids of KLHL24 protein.
This 43S preinitiation complex then scans the 5' UTR of the mRNA, with the help of eIF4A, until an initiation codon in optimal context is recognized [18].
Novel mutation of the initiation codon of PAX9 causes oligodontia.
This mutation, next to the initiation codon, was named as codon 1 by the Huisman Database [betal(NA1) Val>Met] (3).
Perhaps, in PDV/3541UK, GUG can be used as the initiation codon or initiation may take place at the next available Met.

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