Traditional
fate mapping, which is somewhat like developing a family tree for cells, labels cells based on the expression of a certain gene.
Citation: Wataru Kimura etal.' "Hypoxia
fate mapping identifies cycling cardiomyocytes in the adult heart," Nature, 2015; DOI: 10.1038/nature14582
The paper ("Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type", Developmental Cell (31,543-558, 8 December 2014) summarizes research involving in vivo
fate mapping done in an attempt to link hair loss to the roles and fate of various cell populations in and around the hair follicle.
The researchers used "genetic
fate mapping" techniques to make their discovery - a method that tracks the development of stem cells and cells derived from them, at desired time points during the life of an animal.