The concentration-response curve for antiestrogenic activity overlapped with the concentration-response curve for mitochondrial [O.sub.2] consumption inhibition in osteosarcoma
cybrids after 10 min of incubation with CPC (Figure 4A).
Wong, "Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial
cybrids," Annals of the New York Academy of Sciences, vol.
In line with this defect, elevated levels of ROS were also observed in LHON
cybrids in vitro, harboring any of the three primary LHON mutations [14-17].
We cultured transmitochondrial
cybrids in high-glucose (4.5 g/L) Dulbecco's modified Eagle's medium (DMEM).
In sum, over the past thirty years we have seen a process that has displaced the axiomatic status of natural facts, and has prepared the ground for new understandings and applications of these 'facts' - often simply the ability to direct their function - which have then been used to propagate new biological entities, such as cultured stem cell colonies,
cybrids and induced pluripotent embryoid bodies.
Protoplast-fusion derived Solanum
cybrids: application limitations; phylogenetic limitations.
First, preemptive banning is not "flexible and dynamic," but rigid--it cuts off debate, and with it an avenue for "informed opinions." Had a ban on hybrids and chimeras been in effect in the United Kingdom, for example, regulators there would have had no incentive to conduct the consultation they recently sponsored to explore the ethical and scientific dimensions of creating
cybrids (human nuclei, animal eggs) for research purposes.
Inheritance of organelle genomes in citrus somatic
cybrids. Molecular Breeding, Dordrecht, v.6, p.401405, 2000.
At least two British teams have already applied for licenses to create "cytoplasmic hybrids" or "
cybrids," in which human DNA is added to an empty animal egg to form an embryo that is 99.9 percent human.
Take
cybrids, those hybrids of physical and electronic ...