LY-255582
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| Names | |
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| Preferred IUPAC name
3-{(3R,4R)-1-[(3S)-3-Cyclohexyl-3-hydroxypropyl]-3,4-dimethylpiperidin-4-yl}phenol | |
| Identifiers | |
3D model (JSmol) |
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CompTox Dashboard (EPA) |
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| Properties | |
| C22H35NO2 | |
| Molar mass | 345.527g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25°C [77°F], 100kPa).
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Chemical compound
LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]
See also
[edit ]References
[edit ]- ↑ Dhaher R, et al. (Feb 2012). "Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats". Alcohol (Fayetteville, N.Y.). 46 (1): 17–27. doi:10.1016/j.alcohol.2011年08月01日1. PMC 4581853 . PMID 21962974.
- ↑ Shaw WN, et al. (Jun 1991). "The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat". International Journal of Obesity. 15 (6): 387–95. PMID 1653188.