Gamma-glutamyltransferase 7
From Wikipedia, the free encyclopedia
(Redirected from GGTL3)
Protein-coding gene in the species Homo sapiens
| GGT7 | |||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | GGT7 , D20S101, GGT4, GGTL3, GGTL5, dJ18C9.2, gamma-glutamyltransferase 7 | ||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 612342; MGI: 1913385; HomoloGene: 70866; GeneCards: GGT7; OMA:GGT7 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||
| EC number | 3.4.19.13 | ||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||
Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7 gene.[5] [6] [7]
Function
[edit ]Gamma-glutamyltransferase is a membrane-associated protein involved in both glutathione metabolism and the transpeptidation of amino acids. Changes in gamma-glutamyltransferase activity may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.[7]
References
[edit ]- ^ a b c GRCh38: Ensembl release 89: ENSG00000131067 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027603 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA (August 1993). "Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes". Genomics. 17 (2): 299–305. doi:10.1006/geno.1993.1325. PMID 8104871.
- ^ Heisterkamp N, Groffen J, Warburton D, Sneddon TP (May 2008). "The human gamma-glutamyltransferase gene family". Human Genetics. 123 (4): 321–32. doi:10.1007/s00439-008-0487-7. PMID 18357469. S2CID 15916758.
- ^ a b "Entrez Gene: GGTL3 gamma-glutamyltransferase-like 3".
Further reading
[edit ]- Jikuya H, Takano J, Kikuno R, Hirosawa M, Nagase T, Nomura N, Ohara O (February 2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Research. 10 (1): 49–57. doi:10.1093/dnares/10.1.49 . PMID 12693554.
- Llamazares M, Cal S, Quesada V, López-Otín C (April 2003). "Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain". The Journal of Biological Chemistry. 278 (15): 13382–9. doi:10.1074/jbc.M211900200 . PMC 6066313 . PMID 12562771.
- He X, Di Y, Li J, Xie Y, Tang Y, Zhang F, Wei L, Zhang Y, Qin W, Huo K, Li Y, Wan D, Gu J (September 2002). "Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism". Biochemical and Biophysical Research Communications. 297 (3): 528–36. doi:10.1016/S0006-291X(02)02227-1. PMID 12270127.
Stub icon
This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by adding missing information.