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End-diastolic volume

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Measurement of blood volume
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In cardiovascular physiology, end-diastolic volume (EDV) is the volume of blood in the right or left ventricle at the end of filling during diastole, the relaxation phase of the cardiac cycle.[1] Because greater EDVs cause greater distention of the ventricle, EDV is often used synonymously with preload , which refers to the length of the sarcomeres in cardiac muscle prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole (stroke volume).[citation needed ]


Sample values

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Ventricular volumes
Measure Right ventricle Left ventricle
End-diastolic volume 144 mL (± 23 mL)[2] 142 mL (± 21 mL)[3]
End-diastolic volume / body surface area (mL/m2) 78 mL/m2 (± 11 mL/m2)[2] 78 mL/m2 (± 8.8 mL/m2)[3]
End-systolic volume 50 mL (± 14 mL)[2] 47 mL (± 10 mL)[3]
End-systolic volume / body surface area (mL/m2) 27 mL/m2 (± 7 mL/m2)[2] 26 mL/m2 (± 5.1 mL/m2)[3]
Stroke volume 94 mL (± 15 mL)[2] 95 mL (± 14 mL)[3]
Stroke volume / body surface area (mL/m2) 51 mL/m2 (± 7 mL/m2)[2] 52 mL/m2 (± 6.2 mL/m2)[3]
Ejection fraction 66% (± 6%)[2] 67% (± 4.6%)[3]
Heart rate 60–100 bpm [4] 60–100 bpm [4]
Cardiac output 4.0–8.0 L/minute [5] 4.0–8.0 L/minute [5]

The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL.[5] The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/BSA and ranges between 60 and 100 mL/m2.[5]

See also

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References

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  1. Feger, Joachim (11 November 2020). "End-diastolic volume | Radiology Reference Article | Radiopaedia.org". Radiopaedia. Retrieved 8 August 2022.
  2. 1 2 3 4 5 6 7 Maceira AM, Prasad SK, Khan M, Pennell DJ (December 2006). "Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance" (PDF). European Heart Journal. 27 (23): 2879–88. doi:10.1093/eurheartj/ehl336. PMID 17088316.
  3. 1 2 3 4 5 6 7 Maceira A (2006). "Normalized Left Ventricular Systolic and Diastolic Function by Steady State Free Precession Cardiovascular Magnetic Resonance". Journal of Cardiovascular Magnetic Resonance. 8: 417–426. doi:10.1080/10976640600572889. (subscription required)
  4. 1 2 Normal ranges for heart rate are among the narrowest limits between bradycardia and tachycardia. See the Bradycardia and Tachycardia articles for more detailed limits.
  5. 1 2 3 4 "Normal Hemodynamic Parameters – Adult" (PDF). Edwards Lifesciences LLC. 2009.

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