Adaprolol
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Chemical compound
Pharmaceutical compound
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| Formula | C26H39NO4 |
| Molar mass | 429.601g·mol−1 |
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Adaprolol is a potent beta-adrenergic antagonist.[1] [2] [3] The drug produces electrophysiologic effects, prolonging basic sinus cycle length and the refractory period of the His-Purkinje system and the ventricles of the heart.[4] It is a soft drug purposed for the treatment of glaucoma. The drug was designed to be quickly and easily metabolized, minimizing systemic activity through facile inactivation into an inactive metabolite.[3]
References
[edit ]- ↑ "The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived from the original on March 7, 2012.
- ↑ Boder N, Elkoussi A, Zuobi K, Kovacs P (1996). "Synthesis and pharmacological activity of adaprolol enantiomers: a new soft drug for treating glaucoma". Journal of Ocular Pharmacology and Therapeutics. 12 (2): 115–22. doi:10.1089/jop.1996年12月11日5. PMID 8773927.
- 1 2 "NCATS Inxight Drugs — ADAPROLOL". drugs.ncats.io. Retrieved 2026年05月21日.
- ↑ "Cardiac electrophysiologic effects of adaprolol maleate, a new β-blocker, in closed chest dogs" . Life Sciences. 48 (16): 1519–1528. 1991年01月01日. doi:10.1016/0024-3205(91)90276-H. ISSN 0024-3205.
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