Girolline
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| Names | |
|---|---|
| IUPAC name
(1S,2S)-3-Amino-1-(2-amino-1H-imidazol-5-yl)-2-chloropropan-1-ol | |
| Other names
Giracodazole | |
| Identifiers | |
3D model (JSmol) |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C6H11ClN4O | |
| Molar mass | 190.63g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25°C [77°F], 100kPa).
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Chemical compound
Girolline (also known as giracodazole) is a chemical compound isolated from a marine sponge. It inhibits protein synthesis.[1]
References
- ↑ Fung, S. Y.; Sofiyev, V.; Schneiderman, J.; Hirschfeld, A. F.; Victor, R. E.; Woods, K.; Piotrowski, J. S.; Deshpande, R.; Li, S. C.; De Voogd, N. J.; Myers, C. L.; Boone, C.; Andersen, R. J.; Turvey, S. E. (2014). "Unbiased Screening of Marine Sponge Extracts for Anti-inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis". ACS Chemical Biology. 9 (1): 247–257. doi:10.1021/cb400740c. PMC 4371607 . PMID 24117378.
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