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'''Pikachurin''' is an [[extracellular matrix]]-like [[retina]]l protein first described in 2008 in Japan by (削除) Sato (削除ここまで) (削除) S. (削除ここまで) et al, and named after [[Pikachu]], the highly popular and official mascot of [[Pokémon]].<!--
'''Pikachurin''' is an [[extracellular matrix]]-like [[retina]]l protein first described in 2008 in Japan by (追記) Shigeru (追記ここまで) (追記) Sato (追記ここまで) et al, and named after [[Pikachu]], the highly popular and official mascot of [[Pokémon]].<!--


--><ref name="pmid18641643">{{cite journal |author=Sato S, Omori Y, Katoh K, ''et al'' |title=Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation |journal=[[Nat. Neurosci.]] |volume=11 |issue=8 |pages=923–931 |year=2008 |month=August |pmid=18641643 |doi=10.1038/nn.2160 |url=http://dx.doi.org/10.1038/nn.2160}}</ref><!--
--><ref name="pmid18641643">{{cite journal |author=Sato S, Omori Y, Katoh K, ''et al'' |title=Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation |journal=[[Nat. Neurosci.]] |volume=11 |issue=8 |pages=923–931 |year=2008 |month=August |pmid=18641643 |doi=10.1038/nn.2160 |url=http://dx.doi.org/10.1038/nn.2160}}</ref><!--

Revision as of 17:01, 23 December 2008

Pikachurin is an extracellular matrix-like retinal protein first described in 2008 in Japan by Shigeru Sato et al, and named after Pikachu, the highly popular and official mascot of Pokémon.[1] The protein is colocalized with both dystrophin and dystroglycan at the ribbon synapses.

Pikachurin is necessary for the eyes to track moving objects, and Pikachurin-null mice were unable to track moving objects with their eyes.

Pikachurin is a dystroglycan-interacting protein which has an essential role in the precise interactions between the photoreceptor ribbon synapse and the bipolar dendrites.

See also

References

  1. ^ Sato S, Omori Y, Katoh K; et al. (2008). "Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation". Nat. Neurosci. 11 (8): 923–931. doi:10.1038/nn.2160. PMID 18641643. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
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